Are you looking for best severe cold medicine, we’ve consulted top experts who has in-and-out knowledge about the severe cold medicine. We choose the top most quality product, which comes with amazing features you’ve never heard before. We have filter more than 100+ of product to give you top 10 list of best severe cold medicine.

This list is undoubtedly the best severe cold medicine available in the market today. However, if you don’t want to spend more time on filtering and finding which one is good severe cold medicine, then you should absolutely go for our Top list of the winner. which comes with all the basic features one could expect in a severe cold medicine.


Best severe cold medicine – The Winners!


But these three has some more competitions too, Check out below List of Top 10 best severe cold medicine.If you are ready to choose a new severe cold medicine, check out our recommendations for the best severe cold medicine. But if you’d like to learn more about the various types of severe cold medicine available and how to choose the right one for you, read on.

List of Top 10 Best severe cold medicine In Detailed


SaleBestseller No. 1
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
  • 24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. From the #1 doctor recommended pain relief brand, the combo pack includes 16 Daytime and 8 Nighttime caplets for relief any time of the day
  • The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
  • The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion and pressure
  • Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
  • The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine.
SaleBestseller No. 2
Vicks DayQuil and NyQuil Severe, Cough, Cold, Flu, Sore Throat, Fever, and Congestion Day and Night Relief, Maximum Strength, Green & Red, 48 Count (32 DayQuil + 16 NyQuil)
  • MAXIMUM STRENGTH COLD & FLU RELIEF. DayQuil/NyQuil SEVERE delivers maximum symptom-fighting ingredients to relieve your worst cold & flu symptoms, such as cough, sore throat, fever, and congestion, day or night
  • SMALLEST BRANDED, 4-ACTIVE, MAXIMUM STRENGTH DAYTIME LIQUICAPS. DayQuil SEVERE offers non-drowsy relief of your cold and flu symptoms, so you can power through your day. Guaifenesin helps Loosen Phlegm (Mucus) And Thin Bronchial Secretions To Rid The Bronchial Passageways Of Bothe
  • OUR SMALLEST MOST POWERFUL NIGHTTIME LIQUICAP. NyQuil SEVERE relieves your sneezing, sore throat, headache, minor aches & pains, fever, runny nose, and cough, so you can get the rest you need
  • PAIN RELIEF & FEVER REDUCER. DayQuil/NyQuil SEVERE is an over-the-counter medicine that contains acetaminophen, a pain reliever and fever reducer that can help soothe sore throat
  • MULTI-SYMPTOM RELIEF with NyQuil SEVERE Cold & Flu, which also contains a nasal decongestant and DayQuil SEVERE Cold & Flu, which contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
SaleBestseller No. 3
Vicks NyQuil SEVERE, Nighttime Relief of Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, Berry Flavor, Twin Pack, 12 FL OZ
  • MAX STRENGTH NIGHTTIME RELIEF. NyQuil SEVERE Cold & Flu Liquid temporarily relieves common cold & flu symptoms, including cough due to minor throat & bronchial irritation, sore throat, headache, minor aches & pains, fever, runny nose & sneezing
  • MAXIMUM SYMPTOM-FIGHTING INGREDIENTS to relieve your worst cold & flu symptoms, among OTC cold & flu medicines
  • FROM THE WORLD’S #1 SELLING COUGH & COLD BRAND. Vicks NyQuil SEVERE helps dry up your nasal passages to relieve your runny nose
  • MULTI-SYMPTOM RELIEF. NyQuil SEVERE Cold & Flu contains a nasal decongestant for your toughest nasal congestion and sinus pressure
  • CONTAINS ACETAMINOPHEN: A pain reliever/fever reducer than can help soothe your sore throat
Bestseller No. 4
Theraflu Multi-Symptom Severe Cold and Theraflu Nighttime Severe Cold and Cough Hot Liquid Powder Combo Pack 12 count Box
  • Includes our most popular daytime and nighttime hot liquids formulas - Theraflu Multi-Symptom Severe Cold and Theraflu Nighttime Severe Cold and Cough Hot Liquid Powder Combo Pack to treat your symptoms during day and night
  • The hot liquid provides a soothing effect. Perfect for day or night
  • For adults and children 12 years of age and over. Tackles your worst cold, flu and cough symptoms
  • Theraflu Multi-Symptom Severe Cold comes in refreshing green tea and honey lemon flavors
  • Theraflu Nighttime Severe Cold and Cough comes in soothing honey lemon, chamomile, and white tea flavors
  • Both can be taken every 4 hours, while symptoms persist. Do not take more than 5 packets in 24 hours unless directed by a doctor
  • Theraflu Multi-Symptom Severe Cold formula contains Acetaminophen 500 mg, Dextromethorphan HBr 20 mg, and Phenylephrine HCI 10 mg
  • Theraflu Nighttime Severe Cold and Cough formula contains Acetaminophen 650 mg, Diphenhydramine HCl 25 mg, and Phenylephrine HCI 10 mg
SaleBestseller No. 5
Vicks DayQuil & NyQuil LiquiCaps, Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, Day & Night Relief, 72 LiquiCaps (48 DayQuil, 24 NyQuil)
  • Powerful cold symptom relief, day or night. Get powerful 6-symptom relief with DayQuil/NyQuil LiquiCaps
  • Dayquil non-drowsy, multi-symptom daytime relief. Temporarily relieves common cold & Flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
  • Nyquil nighttime relief. Temporarily relieves common cold & Flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and Pains, fever, runny nose and sneezing so you can sleep
  • #1 Pharmacist recommended over-the-counter cold & Cough medicine from Vicks, the world’s #1 Selling cough & Cold brand
  • Multi-symptom relief with NyQuil Cold & Flu, which also contains a nasal decongestant and DayQuil cold & Flu, which contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
Bestseller No. 6
Vicks NyQuil LiquiCaps, Nighttime Relief of Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, 48 LiquiCaps
  • POWERFUL NIGHTTIME RELEIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold and flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing
  • RELIEVES YOUR COLD SYMPTOMS SO YOU CAN SLEEP BETTER. NyQuil helps to relieve your cold & flu symptoms, so you can get the rest you need
  • #1 PHARMACIST RECOMMENDED over-the-counter cold & cough medicine from Vicks, the world’s #1 selling cough & cold brand
  • MULTI-SYMPTOM RELIEF. NyQuil Cold & Flu contains a nasal decongestant for your toughest nasal congestion and sinus pressure
  • CONTAINS ACETAMINOPHEN: A pain reliever/fever reducer than can help soothe your sore throat
SaleBestseller No. 7
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
  • 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
Bestseller No. 8
Rite Aid Severe Flu and Cold Relief Caplets - 24 Count | Pain Relief | Congestion Relief | Fever Reducer | Sinus Medicine for Adults | Decongestants for Adults | Cold and Flu Medicine for Adults
  • MULTI-SYMPTOM RELIEF: You’ll feel relief from headache, fever, sore throat, nasal congestion, cough, mucus, and chest congestion with Rite Aid. Compare Rite Aid Pharmacy’s Severe Cold & Flu caplets to the active ingredients in top national brands.
  • FOR YOUR SEVERE SYMPTOMS: With Rite Aid Severe Cold & Flu sinus medicine for adults, you’ll get a pain reliever/fever reducer, cough suppressant to calm your cough, expectorant to power through mucus, and nasal decongestants for adults for congestion.
  • FEVER & PAIN RELIEVER: 325mg of Acetaminophen in each caplet temporarily relieves common cold symptoms like minor aches and pains, headache, sore throat and fever. While our cough suppressant and nasal decongestant clear your cough and congestion.
  • COOL BLAST: You’ll know it’s working when you feel the cool blast flavor. Rite Aid’s Severe Cold & Flu has Acetaminophen 325mg; cough suppressant, Dextromethorphan HBr 10mg; expectorant, Guaifenesin 200mg; and nasal decongestant, Phenylephrine HCI 5mg.
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
SaleBestseller No. 9
Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Liquid Medicine, 12 fl oz, Maximum Strength All in One Multi Symptom Relief for Congestion, Sore Throat, Headache,Cough and Reduces Fever
  • MUCINEX FAST-MAX: Maximum strength multi-symptom relief medicine; 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful relief of Mucinex
  • DAY TIME SYMPTOMS TREATED: Maximum strength day time cold and flu non-drowsy liquid relieves cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, fever, body pain & headache and sore throat
  • NIGHT TIME SYMPTOMS TREATED: Maximum strength night time cold and flu liquid relieves cough, nasal congestion that leads to stuffy nose, fever, body pain & headache, sneezing, runny nose and sore & itchy throat
  • DAY TIME ACTIVE INGREDIENTS per 20 mL: Acetaminophen - 650 mg pain reliever and fever reducer; Phenylephrine HCI - 10 mg nasal decongestant; Dextromethorphan HBr - 20 mg cough suppressant; Guaifenesin - 400 mg expectorant/thins and loosens mucus
  • NIGHT TIME ACTIVE INGREDIENTS per 20 mL: Acetaminophen - 650 mg pain reliever and fever reducer; Phenylephrine HCI - 10 mg nasal decongestant; Diphenhydramine HCI - 25 mg cough suppressant/antihistamine
  • FAST ACTING LIQUID: 2 bottles 6 fl oz each; adults and children 12 years of age and older, 20 ml in provided dosing cup every 4 hours
  • TRUST MUCINEX: Mucinex is the No.1 Cold & Cough Brand Doctors Trust for Themselves & Their Families
Bestseller No. 10
Theraflu Daytime Severe Cold and Flu Medicine for Adults and Children 12+, Original Version Berry 8 Count (Pack of 1)
  • Package contains eight Theraflu PowerPods Daytime Severe Cold and Flu Medicine for Adults and Children 12+
  • Theraflu daytime cold medicine for adults and children 12+ can be used as a nasal decongestant, pain and fever reducer or sore throat medicine
  • Quick and easy-to-use PowerPods brew cold and flu medicine with press of a button
  • Medicinal cough medicine pods work easily with single-serve coffee machines
  • Berry-flavored cold and flu remedy infused with menthol and green tea flavors for pleasant relief
  • Daytime formula includes acetaminophen for powerful relief without drowsiness
  • Fill single-serve machine with eight ounces of water then insert pod to brew instantly
  • HSA and FSA eligible product
Hope this list of the best severe cold medicine will be helpful for you. Feel free to contact us if you have any questions about our site or our reviews, and we will be happy to help you with your purchasing decisions in any way we can.